Table 1. Immunostaining of human RCC tumours from BHD patients.
Tissue | pERK | pS6 |
---|---|---|
Normal kidney parenchyma | Glomeruli and collecting ducts are positive | |
Patient 1—RCC chromophobe | ++ | +/− |
*Patient 2—RCC clear cell | ++ | ++ |
*Patient 2—RCC oncocytoma | ++ | ++ |
†Patient 3—RCC oncocytoma | — | — |
†Patient 3—RCC chromophilic | + | — |
Patient 4—chromophobe/oncocytoma hybrid | ++ | +/− |
++, strongly positive in a large percentage of the tumour; +, positive, +/−, focal areas of positivity.
*Denotes tumours from the same patient.
†Denotes tumours from the same patient.