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(a–f) The barrier and MFPT results when γcancer->cancer, Dcancer as well as the diffusion coefficient change; Barriers1n, the barrier between s1 and the normal state. Barriers1l, the barrier between s1 and the low cancer state. τln, the mean first passage time from the low cancer state to the normal state. τnl, the mean first passage time from the normal state to the low cancer state.
