Table 2.
Features of the 25 most abundant differentially accumulated representative RNA fragments
| Sequence | Length | Parental RNA | RNA class | Fragment type | log2FC 72 hpia | log2FC 96 hpia | Relative abundance | |||
|---|---|---|---|---|---|---|---|---|---|---|
| 72C | 72I | 96C | 96I | |||||||
| CCCCCCACUGCUAAAUUUGACUG | 23 | hy4 Ro RNA | Y RNA | Ro60 binding region | 2.00 | 3.01 | 4.03% | 16.11% | 5.51% | 44.43% |
| UCCCACAUGGUCUAGCGGUUAGGAUUCCUGGUU | 33 | tRNA, TTC (Glu) | tRNA | tRF-5A | 2.14 | 2.43 | 2.10% | 9.25% | 2.76% | 14.90% |
| UCCCUGGUGGUCUAG | 15 | tRNA, CTC (Glu) | tRNA | tRF-5D | 3.04 | 1.41 | 0.27% | 2.25% | 0.86% | 2.29% |
| UACGACUCUUAGCGGUGGAUCACUCGGC | 28 | ambiguous mapping (intergenic / rRNA) | other | n/ab | 2.38 | 1.95 | 0.20% | 1.03% | 0.30% | 1.16% |
| GCCCGGCUAGCUCAGUCGGUAGAGCAUGGGACUCUUAAUCCCAGGGUCGUGGGUU | 55 | tRNA, CTT (Lys) | tRNA | tRF-5T | 1.03 | 2.40 | 0.48% | 0.98% | 0.44% | 2.34% |
| GUUAAGAUGGCAGAGCCCGGUAAUCGCAUAAAACUUAAAACU | 42 | tRNA, TAA (Leu) | tRNA | tRF-5A | 0.93 | 2.54 | 0.50% | 0.96% | 0.54% | 3.13% |
| UUGGUCGUGGUUGUAGUCCGUGCGAGAA | 28 | tRNA, TTC (Glu) | tRNA | tRF-Δ5A-Δ3AA | 1.36 | 4.32 | 0.34% | 0.86% | 0.26% | 5.24% |
| GUUCGCGCUUUCCCCUG | 17 | U1 spliceosomal RNA | snRNA | no functional region | 0.61 | 3.56 | 0.54% | 0.83% | 0.21% | 2.46% |
| CGGCCACUGAUUAUCGAGGCGAUUCUGAUCUG | 32 | scaRNA, HBII-382/scaRNA2 | scaRNA | no functional region | 0.80 | 2.62 | 0.46% | 0.80% | 0.57% | 3.52% |
| CCCCACUGCUAAAUUUGACUG | 21 | hy4 Ro RNA | Y RNA | Ro60 binding region | 2.63 | 3.70 | 0.12% | 0.72% | 0.25% | 3.18% |
| ACUCGACUGCAUAAUUUGUGGUAGUGGGG | 29 | U1 spliceosomal RNA | snRNA | Sm binding | 5.22 | 7.82 | 0.02% | 0.58% | 0.03% | 7.43% |
| UAGGAUGGGGUGUGAUAGGUGGCACGGAGAA | 31 | ambiguous mapping (intergenic / tRNA) | other | n/a | 1.38 | 3.55 | 0.21% | 0.54% | 0.17% | 2.05% |
| CACAAAUGAUGAAUAACAAAGGGACU | 26 | C/D box snoRNA, SNORD82/U82 | snoRNA | box C | 2.40 | 3.49 | 0.10% | 0.53% | 0.15% | 1.72% |
| UCCCUGGUGGUCUAGUGGUUAGGAUUCGGCGCUCUCACC | 39 | tRNA, TTC (Glu) | tRNA | tRF-5A | 1.62 | 2.60 | 0.17% | 0.51% | 0.22% | 1.35% |
| GGUUAGCACUCUGGACUC | 18 | tRNA,CTG (Gln) | tRNA | tRF-Δ5D-Δ3A | 3.02 | 2.46 | 0.06% | 0.49% | 0.11% | 0.63% |
| UCGUACGACUCUUAGCGGUGGAUCACUCGGC | 31 | ambiguous mapping (intergenic / rRNA) | other | n/a | 1.98 | 2.37 | 0.12% | 0.46% | 0.14% | 0.74% |
| AAACUCGACUGCAUAAUUUGUGGUAGUGGGGGACU | 35 | U1 spliceosomal RNA | snRNA | Sm binding | 5.70 | 9.02 | 0.01% | 0.40% | 0.01% | 5.00% |
| GUUAAGAUGGCAGAGCCC | 18 | tRNA, TAA (Leu) | tRNA | tRF-5D | 2.07 | 2.31 | 0.09% | 0.38% | 0.22% | 1.07% |
| GGUAAAAUGGCUGAGUGAAGCAUUGGACU | 29 | tRNA, GTA (Tyr) | tRNA | tRF-5A | 1.33 | 2.65 | 0.14% | 0.36% | 0.17% | 1.05% |
| ACUUUAGCUCUAGAAUUACUCUGAGACCU | 29 | C/D box snoRNA, SNORD45/U45 | snoRNA | box D, guide sequence 2 | 2.00 | 5.05 | 0.09% | 0.35% | 0.06% | 2.14% |
| CUACGGGGAUGAUUUUACGAAC | 22 | C/D box snoRNA, SNORD26/U26 | snoRNA | box C | 3.05 | 2.40 | 0.04% | 0.35% | 0.11% | 0.58% |
| UCACCCGGCCCGGACACG | 18 | piRNA | other | n/a | 5.07 | 8.18 | 0.01% | 0.34% | 0.01% | 4.13% |
| AAUGUGGGAAACUCGACUGCAUAAUUUGUGGUAGUGGGGGACU | 43 | U1 spliceosomal RNA | snRNA | Sm binding | 8.36 | 9.93 | 0.00% | 0.34% | 0.00% | 3.09% |
| AUUGGAAGACACUCUGCGACAGUG | 24 | H/ACA box snoRNA, ACA7/SNORA7/SNORA7A | snoRNA | box ACA, guide sequence 4 | 0.97 | 3.22 | 0.17% | 0.33% | 0.18% | 1.64% |
| CACGCAUCGACCUGGUAUUGCAGUACCUCCAGGAACGG | 38 | U2 spliceosomal RNA | snRNA | no functional region | 2.62 | 5.47 | 0.05% | 0.31% | 0.04% | 1.78% |
adifferentially accumulated (log2FC ≥ 2 or ≤ −2 and FDR < 0.05; relative abundance sorted by 72I) are marked with boldtype
bnot applicable