Table 1.
A Summary of Selected Laboratory Variables in the Subjects Studied
| Asthma patients n = 164 |
Control subjects n = 72 |
p value asthma vs. controls |
Allergic asthma n = 94 |
p value allergic asthma vs. controls |
Non-allergic asthma n = 70 |
p value non-allergic asthma vs. controls |
p value allergic vs. non-allergic asthma |
|
|---|---|---|---|---|---|---|---|---|
| hsCRP, mg/l | 1.27 (0.59–2.55) | 0.87 (0.29–2.9) | 0.03 | 1.21 (0.56–2.3) | 0.34 | 1.85 (0.62–2.78) | 0.04 | 0.67 |
| Fibrinogen, g/l | 3.6 (3.0–3.95) | 3.36 (2.73–3.57) | 0.001 | 3.5 (3.0–3.9) | 0.03 | 3.65 (3.1–4.1) | 0.004 | 0.39 |
| α2-macroglobulin, nmol/l | 3.7 (3.23–4.22) | 3.29 (2.89–3.57) | 0.0002 | 3.78 (3.36–4.30) | <0.0001 | 3.54 (3.04–4.22) | 0.02 | 0.22 |
| Platelet factor 4, ng/ml | 146.65 (129.87–156.91) | 97 (87–112.5) | <0.0001 | 148.29 (129.61–157.85) | <0.0001 | 144.96 (130.13–156.49) | <0.0001 | 0.62 |
| Immunoglobulin E, IU/ml | 1.92 (1.37–2.37) | 1.5 (1.39–1.84) | 0.003 | 2.26 (1.91–2.61) | <0.0001 | 1.29 (1.24–1.68) | 0.23 | <0.0001 |
| Eosinophils, /ul | 166 (100–300) | ND | NA | 180 (80–300) | NA | 140 (100–250) | NA | 0.7 |
| Interleukin 6, pg/ml | 4.55 (3.58–5.73) | 3.06 (2.56–4.1) | <0.0001 | 4.43 (3.45–5.6) | <0.0001 | 4.83 (3.87–5.86) | <0.0001 | 0.14 |
| Tumor necrosis factor α, pg/ml | 3.93 (3–4.7) | 2.91 (2.26–3.7) | <0.0001 | 4.02 (3.02–4.75) | <0.0001 | 3.8 (2.91–4.69) | <0.0001 | 0.69 |
| Periostin, ng/ml | 0.44 (0.32–0.6) | ND | NA | 0.41 (0.32–0.56) | NA | 0.45 (0.34–0.7) | NA | 0.3 |
Data is presented as median with upper and lower quartiles
ND not done, NA not applicable, hsCRP high-sensitivity C-reactive protein, n number