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. 2005 Feb 18;33(3):1058–1068. doi: 10.1093/nar/gki237

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© The Author 2005. Published by Oxford University Press. All rights reserved

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The hairpin ribozyme constructs used in this study. (A) Secondary structure of the HF1 and HF16 hairpin ribozyme constructs, with the 2′-NH₂ modified inhibitory substrate strand shown in bold. The arrow indicates the substrate cleavage site. (B) Crystal structure of the HF16 hairpin ribozyme construct (6). The bold arrow indicates the location of the 2′-NH₂ modification.