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eNOS uncoupling in diabetes. (a) Representative Western blot for eNOS as dimer and monomer, and total cardiac eNOS from control (non-diabetic), diabetic and diabetic + exercise rats hearts (diabetic EX), n = 5 hearts each group. (b) Quantification for cardiac levels eNOS. (c) Ratio of dimer to monomer eNOS. (d) Intracardiac levels of tetrahydrobiopterin (BH4). ∗p < 0.05 versus control.
