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. 2017 Jul 1;17:460. doi: 10.1186/s12885-017-3430-2

Fig. 1.

Fig. 1

RanBPM association with HDAC6 is required for inhibition of HDAC6 deacetylase activity. Top, whole cell extracts from RanBPM shRNA Hela cells either left untransfected or transfected with HA-RanBPM-WT or HA-RanBPM-Δ360 were analyzed by western blot with the antibodies indicated. Bottom, quantification of relative amounts of acetylated α-tubulin was normalized to total α-tubulin levels. Relative amounts of acetylated α-tubulin in untransfected and HA-RanBPM-Δ360-transfected cells were normalized to WT. Results are averaged from three different experiments, with error bars indicating SEM. P < 0.05 (*)