Table 1. Serum biochemical data for rabbits treated with OPG-chitosan (group III) or chitosan (group II) gels and untreated control rabbits (group I) at baseline and 6 weeks after treatment.
Parameter | Baseline | 6 weeks | Normal range | ||||
---|---|---|---|---|---|---|---|
Group III | Group II | Group I | Group III | Group II | Group I | ||
Sodium mmol/L | 142 ± 0 | 142 ± 1 | 141 ± 1 | 143 ± 0 | 141 ± 1 | 141 ± 0.7 | 139–146 |
Potassium mmol/L | 4 ± 0.1 | 5 ± 0.4 | 5 ± 0.7 | 3.8 ± 0.1 | 3.95 ± 0.1 | 5 ± 0.6 | 3–5 |
Chloride mmol/L | 103 ± 0.7 | 102 ± 0 | 101.5 ± 0.2 | 100 ± 4.2 | 101 ± 1 | 99.5 ± 4 | 104–116 |
Urea nitrogen mmol/L | 8 ± 0.42 | 7 ± 1.5 | 8 ± 0.2 | 6 ± 1.5 | 7 ± 0.07 | 9 ± 0.07 | 6.35–16 |
Creatinine µmol/L | 77 ± 6 | 78 ± 2 | 77 ± 5 | 102 ± 15 | 77 ± 7 | 85 ± 4 | 60–140 |
Albumin (g/L) | 41 ± 0.0 | 38 ± 1 | 41 ± 1 | 39 ± 4 | 40 ± 4 | 40 ± 1 | 20–40 |
Total Bilirubin (µmol/L) | <2 | <2 | <2 | <2 | <2 | <2 | 2–5 |
Alkaline Phosphate (U/L) | 102 ± 6 | 111 ± 8 | 110 ± 4.9 | 50 ± 10 | 81 ± 3 | 69 ± 3 | 17–192 |
Alanine Aminotransferase (U/L) | 30.5 ± 3 | 94.5 ± 2 | 36 ± 15 | 35 ± 0 | 53 ± 12.7 | 52.5 ± 3.1 | 38–86 |
G-Glutamyl Transferase (U/L) | 5.5 ± 0.7 | 5.5 ± 0.9 | 2.5 ± 0.7 | 6 ± 1.5 | 6.5 ± 1.4 | 5 ± 1.4 | 6–22 |
Triglyceride (mmol/L) | 0.5 ± 0.1 | 0.7 ± 0.1 | 0.65 ± 0.2 | 0.5 ± 0.1 | 0.7 ± 0.15 | 0.75 ± 0 | – |
Total Cholesterol (mmol/L) | 1 ± 0.2 | 0.9 ± 0.1 | 1.1 ± 0 | 1.3 ± 0.3 | 0.85 ± 0.2 | 1.2 ± 0.1 | – |
HDL Cholesterol (mmol/L) | 0.8 ± 0.2 | 0.61 ± 0.1 | 0.8 ± 0.2 | 0.2 ± 0.1 | 0.62 ± 0.1 | 0.8 ± 0.1 | – |
Notes.
Data are expressed as the mean ± SD of three rabbits per group.