Table 2. Serum biochemical data for rabbits treated with OPG-chitosan (group III) or chitosan (group II) gels and untreated control rabbits (group I) at baseline and 12 weeks after treatment.

Parameter	Baseline			12 weeks			Normal range
	Group III	Group II	Group I	Group III	Group II	Group I
Sodium mmol/L	142 ± 2	142 ± 1	143 ±2	142 ± 2.6	143 ± 1	143 ± 2	139.3–145.7
Potassium mmol/L	4 ± 1	4 ± 0.3	4 ± 0.4	4 ± 0.6	4 ± 0.4	4 ± 0.5	3–5
Chloride mmol/L	100 ± 0.5	101 ± 0.6	98 ± 3.5	102 ± 0.2	101 ± 2	104 ± 4	105–116
Urea nitrogen mmol/L	8 ± 1	8 ± 1	9 ± 0.4	8 ± 1	7 ± 1	8 ± 1	6–16
Creatinine µmol/L	85.7 ± 10	87 ± 1	89 ± 2	89 ± 10	83 ± 2	87 ± 1	60–140
Albumin (g/L)	43.3 ± 3	40.7 ± 1	42 ± 1	41 ± 2.9	40 ± 3	39 ± 3	20–41
Total Bilirubin (µmol/L)	<2	<2	<2	<2	<2	<2	2–5
Alkaline Phosphate (U/L)	68.5 ± 12	44 ± 3	69.5 ± 8	58 ± 1	44 ± 9	48 ± 8	17–192
Alanine Aminotransferase (U/L)	58 ± 6.9	60 ± 9.7	48.7 ± 10	53.7 ± 15.8	67 ± 12	54 ± 7	38–86
G-Glutamyl Transferase (U/L)	6 ± 1.2	7 ± 1.5	3 ± 1.4	4 ± 0.6	7 ± 1.7	5 ± 1.2	6.00–22.00
Triglyceride (mmol/L)	0.7 ± 0.5	0.6 ± 0.2	0.4 ± 0.01	1.2 ± 0.2	0.6 ± 0.2	0.5 ± 0.2	–
Total Cholesterol (mmol/L)	1 ± 0.2	1 ± 0.2	1 ± 0.2	1 ± 0.2	1 ± 0.2	1 ± 0.2	–
HDL Cholesterol (mmol/L)	0.7 ± 0.1	0.5 ± 0.03	0.7 ± 0.1	0.9 ± 0.04	0.6 ± 0.1	0.6 ± 0.1	–
LDL Cholesterol (mmol/L)	0.2 ± 0.1	0.2 ± 0.08	0.1 ± 0.1	0.1 ± 0.1	0.2 ± 0.1	0.26 ± 0.1	–

Notes.

Data are expressed as the mean ± SD of three rabbits per group.