Table 1.

Biomarkers of HCC Pathways

Function	Reference
Suppression/modulation of growth	Dargel et al., 2015; Haruyama et al., 2015, 2016
Cytokine which upregulates expression of interferon gamma and interleukin-12	Dong et al., 2016
Membrane protein of the apparatus Golgi expressed in liver and biliary epithelial cells	Ba et al., 2012; Yang et al., 2015
Repair pathways, DNA replication and transcription	Thurnherr et al., 2016
Repair pathways, DNA replication and transcription	Thurnherr et al., 2016
Repair pathways, DNA replication, transcription and autophagy mechanism	Thurnherr et al., 2016
Metabolic pathways and the immune system	Thurnherr et al., 2016
Metabolic pathways and the immune system	Thurnherr et al., 2016
Metabolic pathways and the immune system	Thurnherr et al., 2016
Vascularization	Fish et al., 2009; Fátima and Papa, 2010; Liu et al., 2016
Angiogenesis	Fish et al., 2009; Fátima and Papa, 2010; Liu et al., 2016
Suppressor migration and cell invasion	Fish et al., 2009; Fátima and Papa, 2010; Liu et al., 2016
Cell proliferation and differentiation	Kedmi et al., 2015
Angiogenesis	Shao et al., 2011; Okada et al., 2015
Blockade of the cell cycle and apoptosis	Li et al., 2016
Blockade of the cell cycle	Zhang et al, 2014
Tumor suppressive	Zhang et al., 2014
Angiogenesis	Moeini et al., 2012; Cheng et al., 2016
Proliferation and cell migration	Kedmi et al., 2015
Angiogenesis	Shao et al., 2011; Okada et al., 2015
Cell development, homeostasis and aging	Su et al., 2010; Elmashad et al., 2015; Jung and Suh, 2015
Cell growth, differentiation, proliferation and migration	Li et al., 2016; Buitrago-Molina and Vogel, 2012; Merkenschlager and Marcais, 2015.