Table 1. Patient demographics.
| Parameters | Adult AD | P value | |
|---|---|---|---|
| Pre-adult-onset (< 18 yr; n = 232) | Adult-onset (≥ 18 yr; n = 48) | ||
| Sex (M/F) | 122 (52.6)/110 (47.4) | 29 (60.4)/19 (39.6) | 0.322 |
| Age, yr | 25.987 ± 7.250 (range, 18–56) | 32.708 ± 8.570 (range, 18–54) | < 0.001* |
| Age of onset, yr | 5.766 ± 5.289 | 27.375 ± 7.946 | < 0.001* |
| Duration, yr | 20.42 ± 8.85 | 5.54 ± 5.86 | < 0.001* |
| EASI score | 11.098 ± 8.986 | 10.015 ± 10.630 | 0.495 |
| Serum total IgE, kU/L | 803.300 ± 1,116.852 | 1,172.900 ± 1,114.932 | 0.114 |
| Serum total IgE (≥ 200), kU/L | 113/136 (83.09) | 24/29 (82.76) | 1.000 |
| BMI, kg/m2 | 22.274 ± 3.609 | 23.012 ± 3.658 | 0.206 |
| Obesity (BMI ≥ 25) | 42 (18.1) | 13 (27.1) | 0.209 |
| Habitation | 0.636 | ||
| City | 191 (82.3) | 42 (87.5) | |
| Countryside | 3 (1.3) | 0 (0) | |
| Past medical history | |||
| Allergic rhinitis | 109 (46.9) | 22 (45.8) | 0.884 |
| Asthma | 23 (9.9) | 4 (8.3) | 0.799 |
| History of family atopic disease | 116 (50.0) | 20 (41.7) | 0.293 |
| Allergic rhinitis | - | ||
| Parents | 32 (13.8) | 3 (6.3) | |
| Siblings | 21 (9.1) | 6 (12.6) | |
| Asthma | - | ||
| Parents | 1 (0.4) | 4 (8.3) | |
| Siblings | 1 (0.4) | 2 (4.2) | |
| AD | - | ||
| Parents | 8 (3.4) | 4 (8.3) | |
| Siblings | 32 (13.8) | 6 (12.6) | |
Values are presented as number (%) or mean ± standard deviation.
AD = atopic dermatitis, EASI = Eczema Area and Severity Index, IgE = immunoglobulin E, BMI = body mass index.
*P < 0.001.