Figure 4. Phosphatase‐inactive laforin does not rescue glycogen hyperphosphorylation in Epm2a ^−/− or Epm2b ^−/− brain.

1. Brain glycogen carbon C6 phosphate levels in the presence or absence of WT (.Laf) or C265S mutated (.C265Laf) murine laforin transgene.
2. Brain glycogen C6 phosphate levels of WT, Epm2a ^−/− and Epm2b ^−/− mice in the presence or absence of human C266S mutated laforin (.C266SLaf).

Data information: Data are presented as means of at least five biological replicates ± SEM. Asterisks, statistical significance by ANOVA and post hoc analyses (*P < 0.05, **P < 0.01, ***P < 0.001; Appendix Table S3).