Figure 2. Mpdz‐deficient mice develop hydrocephalus.

1. At postnatal day 27 (P27), Mpdz ^−/− and wild‐type littermates were subjected to a computed tomography. Three‐dimensional reconstruction shows macrocephaly and thinning of skull bones (arrows).
2. T2‐weighted coronal and sagittal magnetic resonance images of the head of Mpdz ^−/− vs. Mpdz ^+/+ mice at P27. CSF in the enlarged lateral ventricles appears hyperintense (asterisks).