Table 3.
Genotype distributions and detailed association results.
| Genotype | IS (n) | Control (n) | OR (95% CI) | p | OR (95% CI)∗ | p ∗ |
|---|---|---|---|---|---|---|
| rs7620580 | ||||||
| AA | 199 | 228 | 1.000 | 1.000 | ||
| AG | 166 | 122 | 1.559 (1.153–2.107) | 0.004 | 1.534 (1.011–2.328) | 0.045 |
| GG | 20 | 12 | 1.910 (0.911–4.004) | 0.087 | 3.195 (1.228–8.312) | 0.017 |
| Recessive | 1.598 (0.770–3.318) | 0.208 | 2.686 (1.049–6.879) | 0.039 | ||
| Additive | 1.490 (1.157–1.919) | 0.002 | 1.636 (1.163–2.300) | 0.005 | ||
| Dominant | 1.590 (1.187–2.130) | 0.002 | 1.662 (1.110–2.487) | 0.014 | ||
| rs2289843 | ||||||
| TT | 101 | 107 | 1.000 | 1.000 | ||
| TA | 195 | 181 | 1.141 (0.813–1.602) | 0.445 | 1.291 (0.809–2.059) | 0.285 |
| AA | 89 | 74 | 1.274 (0.845–1.922) | 0.248 | 1.402 (0.807–2.434) | 0.231 |
| Recessive | 1.170 (0.826–1.658) | 0.377 | 1.197 (0.748–1.914) | 0.453 | ||
| Additive | 1.130 (0.920–1.386) | 0.243 | 1.189 (0.903–1.566) | 0.216 | ||
| Dominant | 1.180 (0.857–1.625) | 0.311 | 1.326 (0.856–2.053) | 0.206 | ||
| rs1708303 | ||||||
| AA | 241 | 260 | 1.000 | 1.000 | ||
| AG | 132 | 94 | 1.515 (1.103–2.081) | 0.010 | 1.610 (1.040–2.490) | 0.033 |
| GG | 12 | 8 | 1.618 (0.650–4.027) | 0.301 | 1.550 (0.484–4.969) | 0.461 |
| Recessive | 1.424 (0.575–3.524) | 0.445 | 1.338 (0.421–4.250) | 0.622 | ||
| Additive | 1.438 (1.092–1.892) | 0.010 | 1.476 (1.020–2.135) | 0.039 | ||
| Dominant | 1.523 (1.119–2.073) | 0.007 | 1.604 (1.051–2.447) | 0.028 |
∗adjusted for age, SBP, DBP, FPG, TG, HDL, LDL, smoking, drinking, and BMI.