Table 2.

Levels of serum biochemical parameters for all groups.

Parameters	Control	RIS	RIS+RSV-1	RIS+RSV-2	RIS+RSV-3	p
Scr (mg/dL)	0.46 ± 0.00b,d,e	0.53 ± 0.00a,c,d,e	0.45 ± 0.01b,d,e	0.38 ± 0.01a,b,c	0.37 ± 0.01a,b,c	0.000
BUN (mg/dL)	18.71 ± 0.68b,d,e	25.85 ± 0.45a,c,d	19.85 ± 0.50b,d,e	23.28 ± 0.42a,b,c	24.57 ± 0.48a,c	0.000

Each group represents the mean ± SEM for seven rats. ^ap < 0.01 versus the control group; ^bp < 0.01 versus the RIS group; ^cp < 0.01 versus the RIS+RSV-1 group; ^dp < 0.01 versus the RIS+RSV-2 group; and ^ep < 0.01 versus the RIS+RSV-3 group. RIS: risperidone; RSV: resveratrol; Scr: serum creatinine; BUN: blood urea nitrogen; RIS+RSV-1: 2 mg/kg RIS+20 mg/kg RSV; RIS+RSV-2: 2 mg/kg RIS+40 mg/kg RSV; RIS+RSV-3: 2 mg/kg RIS+80 mg/kg RSV.