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C5aR2 KO with lipometabolism.
| Source | Disease model | Properties of C5aR2 | Refs |
|---|---|---|---|
| C5aR2 heterozygous mice from Regeneron Pharmaceutics Inc. | Physiological metabolism of C5aR2 KO mice | Stimulates TG synthesis and glucose transport in adipose tissue | [106] |
| Diet induced obesity | Anti-inflammation | [95, 113] | |
| Partial hepatectomy | Promotes liver regeneration | [97] | |
| High fat diet-induced insulin resistance | Anti-inflammation, metabolic regulation | [112] |
