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Coffee reduced KRAS expression in Caco-2 cells. Caco-2 cells were treated with 0–5% coffee for 24 h, and KRAS expression was monitored by (A) western blot and (B) quantitative polymerase chain reaction. **P<0.01 and ***P<0.001 vs. 0% (n=3). KRAS, KRAS proto-oncogene, GTPase.
