Table 1. Sphingolipid content of WT and Galgt1 Siat9 double-null brains.
Sphingolipid | WT 1 | WT 2 | Galgt1 Siat9 DN 1 | Galgt1 Siat9 DN 2 |
---|---|---|---|---|
Cer | 1,200 | 610 | 730 | 300 |
HexosylCer | 4,400 | 4,700 | 4,700 | 7,600 |
LactosylCer | <200 | <200 | 3,700 | 2,700 |
SM4s | 2,200 | 2,000 | 2,800 | 2,700 |
SM3 (LacCer II3-sulfate) | <40 | <40 | 450 | 480 |
Quantitation of ceramide (Cer), hexosylceramide (HexosylCer), lactosylceramide (LactosylCer), SM4s, and SM3 in lipid extracts from two brains from WT mice (WT 1 and 2) and two brains from Galgt1 Siat9 double-null mice (Galgt1Siat9DN 1 and 2). Values are in picomoles of lipid per milligram of wet weight.