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. 2017 May 17;14(1):607–614. doi: 10.3892/ol.2017.6184

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Copyright: © Saralamma et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — FSB-induced apoptosis in AGS cells is independent of the extrinsic apoptotic signaling pathway. (A) AGS cells were treated with the indicated concentrations of FSB for 24 h. The cell lysates were subjected to SDS-PAGE and analyzed by western blotting. β-actin was used as loading control. Protein expression levels of Fas and FasL were determined using densitometric analysis. (B) Caspase-8 activities were determined using a colorimetric caspase-8 activity assay. FSB, flavonoid extract from Korean Scutellaria baicalensis Georgi; Fas, tumor necrosis factor regulator superfamily member 6; FasL, Fas ligand.