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. 2017 May 17;14(1):525–532. doi: 10.3892/ol.2017.6198

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Downregulation of S100P expression inhibits C666-1 cell migration. (A) Sample images showing the results of the Transwell assay that the cells in the S100P-siRNA group that had migrated to the lower Transwell membrane surfaces was reduced compared with the negative control siRNA and untreated control groups. (B) Graphs indicated the average number of cells from five random fields in the three groups (P<0.01). (C) The migration rate was quantified by evaluating the distance between the edges of the scratch in a scratch migration assay. (D) Graphs indicated that the cells in the S100P-siRNA group migrated slowly, compared with those in the negative control siRNA and untreated control groups (P<0.01). **P<0.01. S100P, S100 calcium binding protein P; siRNA, small interfering RNA.