Table II.
Cox regression analysis of clinicopathological factors.
| Clinicopathological factors | Hazard ratio (95% CI) | P-value |
|---|---|---|
| Age, years | 1.03 (1.01–1.04) | 0.003 |
| Sex | ||
| Female | ||
| Male | 0.90 (0.62–1.31) | 0.569 |
| pT stage | 0.291 | |
| 1 | 1.00 | |
| 2 | 0.67 (0.14–3.19) | 0.618 |
| 3 | 0.46 (0.09–2.50) | 0.371 |
| 4 | 0.77 (0.13–4.47) | 0.770 |
| pN stage | ||
| 0 | 1.00 | |
| 1 | 5.17 (1.36–19.59) | 0.016 |
| 2 | 7.01 (1.76–27.96) | 0.006 |
| Venous invasion | ||
| 0 | ||
| 1 | 1.27 (0.72–2.26) | 0.410 |
| Lymphatic invasion | ||
| 0 | ||
| 1 | 0.90 (0.52–1.57) | 0.719 |
| TNM stage | ||
| I | 1.00 | |
| II | 1.83 (0.68–4.99) | 0.234 |
| III | 0.43 (0.12–1.59) | 0.206 |
| IV | 1.24 (0.31–5.00) | 0.761 |
| Ang-2 expression | ||
| 0 | ||
| 1 | 6.78 (4.16–11.05) | <0.001 |
CI, confidence interval; Ang-2, Angiopoietin-2; TNM, tumor-node-metastasis.