Figure 4.

(A) Immunohistochemistry demonstrating that platelets, which aggregate to become a thrombotic skeleton, bind fibrinogen to construct a mesh-like structure (anti-fibrinogen antibody; 1:100 dilution; magnification, ×1,000), which is similar to artificial vena cava filters and known as an intravenous biological filter. (B) (Left) Mode pattern of artificial nest-like inferior vena cava filter. (Inset) Mesh-like structure is a nest-like biological filter in veins under the microscope (magnification, ×400, Masson staining). (C) (Left) Mode pattern of artificial nest-like inferior vena cava filter filled with thrombi. (Inset) Nest-like biological filters formed inside a venous thrombus under the microscope, in which red blood cells are the dominant blood cells found (magnification, ×400, Masson staining). Inset images reproduced with permission (11).