Figure 5.

(A) In colon cancer, a mesh-like structure (anti-fibrinogen antibody; 1:100 dilution; magnification, ×400) was observed in venules (right upper area of this image), and cancer cells were observed in this mesh-like structure (anti-fibrinogen antibody; 1:100 dilution; magnification, ×400). The mesh-like structure was a nest-like biological filter. (B) Pathological findings of cancer tissues revealing cancer cells. An intravenous biological filter (right area of the image) was filled with cancer cells (anti-fibrinogen antibody; 1:100 dilution; magnification, ×400). Inset images reproduced with permission (11).