Table IV.
Positive rate of MIF and CXCL7 in TT, AT and NT through immunohistochemistry.
| MIF | CXCL7 | ||||||
|---|---|---|---|---|---|---|---|
| Tissue type | n | Positive (%) | Negative (%) | P-value | Positive (%) | Negative (%) | P-value |
| TT | 40 | 37 (92.5) | 3 (7.5) | <0.001a | 35 (87.5) | 5 (12.5) | <0.001a |
| AT | 35 | 20 (57.1) | 15 (42.9) | <0.001b | 17 (48.6) | 18 (51.4) | <0.001b |
| NT | 25 | 4 (16.0) | 21 (84.0) | 0.001c | 3 (12.0) | 21 (88.0) | 0.007c |
χ2 test used in comparison among multiple groups, test standard α=0.05; pairwise comparison among three groups, test standard α=0.01, following Bonferroni method rectification.
a
TT vs. AT
b
TT vs. NT
c
AT vs. NT. MIF, macrophage migration inhibitory factor; CXCL7, C-X-C motif ligand 7 chemokine; TT, tumor tissue; AT, adjacent tissue (1 cm from tumor edge); NT, normal tissue (5 cm from tumor edge).