Figure 2.

Effects of miR-215 overexpression on the proliferation and invasion of breast cancer cells. (A) Overexpression of miR-215 was simulated by transfecting miR-215 mimic into MCF-7A and MDA-MB-231 cells. miR-215 expression was measured using the reverse transcription-quantitative polymerase chain reaction 48 h after transfection. (B) Cell proliferation was determined using an MTT assay. MCF-7A and MDA-MB-231 cells transfected with miR-215 mimic exhibited a decreased rate of proliferation compared with cells transfected with NC. (C) miR-215 overexpression decreased the invasive capacity of MCF-7A and MDA-MB-231 cells compared with NC groups. *P<0.05 compared with NC-transfected cells. mirR-215, microRNA-215; NC, negative control.