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. 2017 May 17;14(1):787–791. doi: 10.3892/ol.2017.6180

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Copyright: © Shi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Lymph node biopsies reveal diffuse and sinus proliferation of large lymphocytes with immunoblastic features. (A) H&E stain; magnification, ×40. (B) H&E stain;magnification, ×400. The lymphoma cells were positive for (C) CD45, (D) CD138 and (E) epithelial membrane antigen, and they exhibited (F) granular cytoplasmic anaplastic lymphoma kinase positivity. Stains for (G) CD43 and (H) CD30 were negative. A subset of tumor cells was moderately positive for (I) CD4. (J) CytokeratinAE1/3 staining of neoplastic cells was positive in the last relapsed needle biopsy. (C and J) Immunoperoxidase stain; magnification, ×400. (D, E, F, I) Immunoperoxidase stain; magnification, ×200. (G and H) Immunoperoxidase stain; magnification, ×40. H&E, hematoxylin and eosin; CD, cluster of differentiation.