Table I.

Characteristics of three selected patients with metastatic RCC.

Patient	Gender	Age, years	Diagnosis	TNM stage	Metastasis	First-line TKI
A	Male	60	RCC, clear cell	T3b-N2-M1	Osseous, peritoneal, pulmonary, muscular	Sunitinib
B	Male	63	RCC, clear cell	No primary tumor detectable	Osseous, pulmonary, chest wall	Sunitinib
C	Female	68	RCC, clear cell, sarcomatoid	pT3a-pNx-cM1	Pulmonary, mediastinal lymph nodes	Sunitinib

RCC, renal cell carcinoma; TNM, tumor-node-metastasis; TKI, tyrosine kinase inhibitor.