Skip to main content
. 2005 Feb 14;102(8):2970–2974. doi: 10.1073/pnas.0500153102

Fig. 5.

Fig. 5.

Suppression of COX-2 mRNA level and COX-2 transcriptional activity in a human colon cancer cell line by NO-1886. (A) RT-PCR analysis of mRNA expression levels for COX-1, COX-2, iNOS, PPARγ, and PPARα in DLD-1 cells treated with the indicated dose of TGFα and/or NO-1886. (B) Reporter gene assay for COX-2 promoter-dependent transcriptional activity in DLD-1 cells. All assays were carried out in triplicate, and data are representative of at least two separate experiments. Data are means; bars are SD. **, P < 0.01.