Table 9.
Multiple regression analysis models (stepwise method) with the circulating levels of Sirt4 as dependent variable to estimate the predictive value of the following: (a) food items of PREDIMED questionnaire and PREDIMED score and (b) total energy intake, SFA, n-3 PUFA, vitamin C, and vitamin E.
| Parameters | Multiple regression analysis | |||
|---|---|---|---|---|
| Model 1 | R 2 | β | t | p value |
| PREDIMED score | 0.335 | 0.579 | 4.6 | <0.001 |
| Fruits ≥3 servings/day | 0.442 | 0.368 | 2.8 | 0.009 |
| Variable excluded: other items of PREDIMED score | ||||
|
| ||||
| Model 2 | R 2 | β | t | p value |
| n-3 PUFA | 0.729 | 0.854 | 10.5 | <0.001 |
| Vitamin E | 0.835 | 0.461 | 5.1 | <0.001 |
| Vitamin C | 0.851 | 0.241 | 2.0 | 0.048 |
| Variable excluded: total energy and SFA | ||||
Among adherence to the MD and food items (model 1) and among dietary macronutrient and micronutrient intake (model 2), circulating levels of Sirt4 were well predicted by PREDIMED score and n-3 PUFA. A p value in bold type denotes a significant difference (p < 0.05). Sirt4: sirtuin 4; PREDIMED: PREvención con DIeta MEDiterránea; SFA: saturated fatty acids; PUFA: polyunsaturated fatty acids.