Table I.

Association between RPS4X expression and the clinicopathological characteristics of patients with ICC.

	RPS4X
Clinicopathological characteristic	Low	High	P-value
Age, years			0.138
<52	40	61
>52	50	50
Gender			0.403
Male	68	78
Female	22	33
Liver cirrhosis status			0.138
Absent	56	80
Present	34	31
Serum CEA, µg/l			0.721
<5	72	91
>5	18	20
Serum CA19-9, U/ml			0.573
≤37	41	55
>37	49	56
Serum ALT, U/l			0.172
≤75	80	91
>75	10	20
Serum GGT, U/l			0.180
≤50	36	34
>50	54	76
Serum ALP, U/l			0.031a
<119	29	52
>119	61	58
Tumor size, cm			0.944
≤5	32	40
>5	58	71
Tumor number			0.487
Single	72	93
Multiple	18	18
Microvascular invasion status			0.662
Absent	59	76
Present	31	35
TNM stage			0.899
I	41	50
II	34	45
III	3	2
IV	12	14

^aP<0.05. ICC, intrahepatic cholangiocarcinoma; RPS4X, X-linked ribosomal protein S4; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19–9; ALT, alanine transaminase; GGT, γ-glutamyl transpeptidase; ALP, alkaline phosphatase; TNM, tumor node metastasis.