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. Author manuscript; available in PMC: 2017 Jul 3.
Published in final edited form as: Cancer. 2014 Apr 15;120(13):1960–1967. doi: 10.1002/cncr.28662

Table 2. Personal and Family History of Patients with PDAC Who Underwent Genetic Testing.

A total of 7 patients with PDAC were found to have mutations in BRCA1 or BRCA2.

BRCA1 Mutation Carriers BRCA2 Mutation Carriers No BRCA Mutation
Number of Subjects 2 5 25
Ashkenazi Jewish Subjects 2 (100%) 3 (60%) 21 (84%)
Mean Age at Diagnosis (Years +/- SD) 49.0 +/- 1.4 58.4 +/- 8.9 61.5 +/- 12.0
Tobacco Use 0 0 3 current, 10 previous
Heavy Alcohol Use 0 0 2
Personal History of Non-PDAC Cancer 0 Breast Cancer in 2 Breast Cancer in 3 Prostate Cancer in 2 Basal Cell Carcinoma in 1 Neuroendocrine in 1
Number of Patients With First-Degree Relatives with PDAC 0 0* 4
Number of Patients with First-Degree Relatives with Breast or Ovarian Cancer 1 2 5
*

One individual had 3 third-degree relatives with PDAC.