Table I.
Patients' characteristics, and univariate analysis of clinicopathologic variables in relation to Glasgow prognostic score after elective hepatic resection for hepatocellular carcinoma.
| Glasgow prognostic score | |||||
|---|---|---|---|---|---|
| P-value (univariate) | |||||
| Factor | All patients | 0 (n=76) | 1 (n=58) | 2 (n=10) | |
| Age (years) | 63 (57–71)a | 63 (56–68) | 66 (58–72) | 66 (62–71) | 0.246 |
| Sex (male:female) | 125:19 | 66:10 | 49:9 | 10:0 | 0.408 |
| Body mass index | 23.3 (21.3–25.4) | 22.9 (21.2–25.4) | 23.3 (21.5–25.0) | 25.3 (23.8–26.9) | 0.159 |
| Hepatitis virus (HBV:HCV:none) | 38:55:51 | 23:32:21 | 13:21:24 | 2:2:6 | 0.218 |
| Child classification (A:B) | 134:10 | 74:2 | 52:6 | 8:2 | 0.053 |
| ICGR15 (%) | 12 (8–19) | 12 (8–16) | 13 (9–23) | 13 (8–21) | 0.149 |
| Serum α-fetoprotein (ng/ml) | 13.7 (5–119.5) | 11 (4.8–26.2) | 38 (6.7–330.0) | 21.5 (10.9–36.7) | 0.183 |
| Type of resection (anatomical:partial) | 78:66 | 43:33 | 30:28 | 5:5 | 0.824 |
| Duration of operation (min) | 371 (262–480) | 377 (239–480) | 368 (285–473) | 315 (263–452) | 0.692 |
| Intraoperative blood loss (g) | 682 (308–1403) | 622 (325–1136) | 1,018 (352–1,845) | 360 (183–760) | 0.125 |
| RC transfusion (present:absent) | 33:111 | 13:63 | 18:40 | 2:8 | 0.160 |
| FFP transfusion (present:absent) | 26:118 | 12:64 | 12:46 | 2:8 | 0.755 |
| Tumor diameter (cm) | 3.2 (2.2–5.5) | 3.0 (2.2–4.2) | 4.0 (2.4–7.4) | 4.0 (2.6–8.2) | 0.002 |
| Tumor number (single:double:triple or more) | 114:13:17 | 62:9:5 | 43:4:11 | 9:0:1 | 0.161 |
| Portal or venous invasion (positive:negative) | 33:111 | 15:61 | 16:42 | 2:8 | 0.549 |
| Coexistent disease | |||||
| Hypertension (present:absent) | 64:80 | 34:42 | 27:31 | 3:7 | 0.621 |
| Diabetes mellitus (present:absent) | 40:104 | 19:57 | 14:44 | 7:3 | 0.008 |
| Hyperlipidemia (present:absent) | 18:126 | 10:66 | 6:52 | 2:8 | 0.673 |
| Postoperative complications | |||||
| Pulmonary complications (present:absent) | 11:133 | 5:71 | 4:54 | 2:8 | 0.312 |
| Massive ascites (present:absent) | 7:137 | 3:73 | 4:54 | 0:10 | 0.558 |
| Biliary leakage (present:absent) | 12:132 | 3:73 | 7:51 | 2:8 | 0.093 |
| Surgical site infection (present:absent) | 11:133 | 4:72 | 4:54 | 3:7 | 0.021 |
a
median (25–75 percentile). GPS, Glasgow prognostic score; HBV, hepatitis B virus; HCV, hepatitis C virus; ICGR15, retention rate of indocyanine green at 15 min; RC, red cell concentrate; FFP, fresh frozen plasma.