Table I.
Correlations between PAK5 expression and clinicopathological factors of patients with gastric cancer.
PAK5 expression | ||||
---|---|---|---|---|
Clinicopathological factors | Patients, n | Low (n=235) | High (n=44) | P-value |
Age | ||||
≥70 years | 110 | 92 | 18 | 0.826 |
<70 years | 169 | 143 | 26 | |
Sex | ||||
Male | 213 | 174 | 39 | 0.037 |
Female | 66 | 61 | 5 | |
Location | ||||
L, M | 224 | 192 | 32 | 0.170 |
U | 55 | 43 | 12 | |
Pathological type | ||||
Differentiated | 129 | 97 | 32 | <0.001 |
Undifferentiated | 150 | 138 | 12 | |
Depth of invasion | ||||
T1 | 116 | 110 | 6 | <0.001 |
T2/T3/T4 | 163 | 125 | 38 | |
Lymph node metastasis | ||||
N0 | 144 | 132 | 12 | <0.001 |
N1/N2/N3 | 135 | 103 | 32 | |
Distant metastasis or recurrence | ||||
Negative | 195 | 170 | 25 | 0.038 |
Positive | 84 | 65 | 19 | |
Stage | ||||
I | 133 | 122 | 11 | 0.001 |
II/III/IV | 146 | 113 | 33 |
PAK5, P21-activated kinase 5. L, lower third of the stomach; M, middle third of the stomach; U, upper third of the stomach.