Table II.
Prognostic factors in univariate and multivariate Cox's proportional hazard regression models for DSS.
| Univariate (Log-rank) | Multivariate | ||||
|---|---|---|---|---|---|
| Clinicopathological factors | 5-year DSS (%) | P-value | HR | 95% CI | P-value |
| Age | |||||
| ≥70 years | 67 | 0.100 | |||
| <70 years | 75.5 | ||||
| Sex | |||||
| Male | 75.6 | 0.878 | |||
| Female | 67.1 | ||||
| Location | |||||
| L, M | 76.5 | 0.020 | 1 | 0.029 | |
| U | 58.1 | 1.74 | 1.06–2.85 | ||
| Pathological type | |||||
| Differentiated | 81.6 | 0.003 | 1 | 0.447 | |
| Undifferentiated | 65 | 1.21 | 0.74–2.00 | ||
| Depth of invasion | |||||
| T1 | 97.3 | <0.001 | 1 | <0.001 | |
| T2/T3/T4 | 64.7 | 6.60 | 2.29–18.99 | ||
| Lymph node metastasis | |||||
| Negative (N0) | 94.2 | <0.001 | 1 | <0.001 | |
| Positive (N1/2/3) | 57.5 | 5.26 | 2.51–11.04 | ||
| Distant metastasis | |||||
| Negative | 79.4 | <0.001 | 1 | <0.001 | |
| Positive | 0.0 | 5.79 | 3.42–9.81 | ||
| PAK5 | |||||
| Low | 74.8 | 0.014 | 1 | 0.659 | |
| High | 58 | 1.14 | 0.65–2.00 | ||
DSS, disease specific survival; PAK5, P21-activated kinase 5; HR, hazard ratio; CI, confidence interval. L, lower third of the stomach; M, middle third of the stomach; U, upper third of the stomach.