Table III.
Prognostic factors in univariate and multivariate Cox's proportional-hazards regression models for RFI in stage I to III.
| Univariate (Log-rank) | Multivariate | ||||
|---|---|---|---|---|---|
| Clinicopathological factor | 5-year RFI (%) | P-value | HR | 95% CI | P-value |
| Age | |||||
| ≥70 years | 76 | 0.833 | |||
| <70 years | 77.2 | ||||
| Sex | |||||
| Male | 75 | 0.725 | |||
| Female | 76.5 | ||||
| Location | |||||
| L, M | 81.1 | 0.002 | 1 | 0.014 | |
| U | 59.3 | 2.00 | 1.15–3.46 | ||
| Pathological type | |||||
| Differentiated | 84.8 | 0.003 | 1 | 0.310 | |
| Undifferentiated | 69.4 | 1.38 | 0.74–2.55 | ||
| Depth of invasion | |||||
| T1 | 96.5 | <0.001 | 1 | 0.001 | |
| T2/T3/T4 | 61.7 | 6.30 | 2.20–18.06 | ||
| Lymph node metastasis | |||||
| Negative (N0) | 95.0 | <0.001 | 1 | <0.001 | |
| Positive (N1/2/3) | 54.6 | 6.92 | 3.02–15.84 | ||
| PAK5 | |||||
| Low | 79.3 | 0.044 | 1 | 0.909 | |
| High | 65.4 | 0.96 | 0.48–1.91 | ||
RFI, relapse-free interval; PAK5, P21-activated kinase 5; HR, hazard ratio; CI, confidence interval. L, lower third of the stomach; M, middle third of the stomach; U, upper third of the stomach.