Table 2.

Assessment of the methodological quality (Jadad scale) and risk of bias (Cochrane collection) of included studies

Study	Jadad score	Random sequence generation	Allocation concealment	Blinding of participants and personnel	Blinding of outcome assessment	Incomplete outcome data	Selective reporting	Other bias	Overall risk of bias
DENERHTN	5	L	L	H	L	L	L	L	H
DENERVHTA	5	L	L	H	H	L	L	L	H
OSLO	5	L	L	H	U	L	L	L	H
Prague-15	5	L	L	H	L	L	L	L	H
ReSET	6	L	U	L	L	L	L	L	U
SYMPLICITY-FLEX	7	L	L	L	L	L	L	L	L
SYMPLICITY HTN-2	5	L	L	H	H	L	L	H	H
SYMPLICITY HTN-3	7	L	L	L	L	L	L	L	L
SYMPLICITY HTN-Japan	5	L	L	H	H	L	L	L	H

H: High risk; L: Low risk, U: Unclear.