Table 3.
Change in office and ambulatory BP (mmHg)
| Clinical trails | 0 month (R/C) | Change at 6 months (R/C) | Change at 12 months (R/C) | Change at 24 months (R/C) | Change at 36 months (R/C) |
|---|---|---|---|---|---|
| DENERHTN | |||||
| Office SBP | 159.3/155.9 | −15.1/−9.5 | -/- | -/- | -/- |
| Office DBP | 93.3/91.4 | −9.1/−6.0 | -/- | -/- | -/- |
| 24-h SBP | 151.6/146.8 | −15.4/−9.5 | -/- | -/- | -/- |
| 24-h DBP | 90.2/88.8 | –9.7/–6.6 | -/- | -/- | -/- |
| DENERVHTA | |||||
| Office SBP | 168/171.2 | −17.5/−29.4 | -/- | -/- | -/- |
| Office DBP | 89.6/90.2 | −7.5/−12.7 | -/- | -/- | -/- |
| 24-h SBP | 149.2/155.4 | −5.7/−23.6 | -/- | -/- | -/- |
| 24-h DBP | 81.3/80.9 | -3.7/-10.2 | -/- | -/- | -/- |
| OSLO | |||||
| Office SBP | 156/160 | −8/−28 | -/- | -/- | -/- |
| Office DBP | 91/89 | −2.8/–10.8 | -/- | -/- | -/- |
| 24-h SBP | 151/149 | −10/−21 | -/- | -/- | -/- |
| 24-h DBP | -/- | –6.9/−10.8 | -/- | -/- | -/- |
| Prague-15 | |||||
| Office SBP | 159/155 | −12.4/−14.3 | −13.4/−11.3 | −17.7/−14.1 | -/- |
| Office DBP | 92/89 | −7.4/−7.3 | -/- | -/- | -/- |
| 24-h SBP | 149/147 | −8.6/−8.1 | −6.4/−8.2 | −9.1/−10.9 | -/- |
| 24-h DBP | 86/84 | –5.7/−4.5 | -/- | -/- | -/- |
| ReSET | |||||
| Office SBP | 160/166 | -/- | -/- | -/- | -/- |
| Office DBP | 95/90 | -/- | -/- | -/- | -/- |
| 24-h SBP | 152/153 | −3.7/−2.6 | -/- | -/- | -/- |
| 24-h DBP | 91/89 | −1.7/−2.6 | -/- | -/- | -/- |
| SYMPLICITY-FLEX | |||||
| Office SBP | -/- | -/- | -/- | -/- | -/- |
| Office DBP | -/- | -/- | -/- | -/- | -/- |
| 24-h SBP | 140.2/140.4 | −7.0/−3.5 | -/- | -/- | -/- |
| 24-h DBP | 78.2/80.6 | −2.8/−2.1 | -/- | -/- | -/- |
| SYMPLICITY HTN-Japan | |||||
| Office SBP | 181.0/178.7 | –16.6/–7.9 | -/- | -/- | -/- |
| Office DBP | -/- | –5.9/1.0 | -/- | -/- | -/- |
| 24-h SBP | 164.7/163.3 | –7.52/–1.38 | -/- | -/- | -/- |
| 24-h DBP | -/- | −4.2/−0.4 | -/- | -/- | -/- |
| SYMPLICITY HTN-2 | |||||
| Office SBP | 178/178 | –32/–1 | −28.1/- | -/- | −32.7/- |
| Office DBP | 97/98 | −12/0 | −9.7/- | -/- | −13.6/- |
| 24-h SBP | -/- | –11/–3 | -/- | -/- | -/- |
| 24-h DBP | -/- | –7/−1 | -/- | -/- | -/- |
| SYMPLICITY HTN-3 | |||||
| Office SBP | 179.7/180.2 | –14.13/–11.74 | −18.9/−21.4 | -/- | -/- |
| Office DBP | 96.5/98.9 | −6.6/−4.6 | -/- | -/- | -/- |
| 24-h SBP | 159.1/159.5 | –6.75/–4.79 | -/- | -/- | -/- |
| 24-h DBP | 88.0/90.9 | –4.1/−3.1 | -/- | -/- | -/- |
1 mmHg = 0.133 kPa. -: Not applicable; R: Catheter-based renal denervation group; C: Control group; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; BP: Blood pressure.