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. 2017 Jul 5;130(13):1586–1594. doi: 10.4103/0366-6999.208238

Supplementary Table 5.

Sensitivity analysis of 24-h DBP at 6 months

Clinical trials Number of patients (R/C) Pooled effect size in mmHg (95% CI) I2 (%) Phet Pz
All trials pooled 558/404 0.14 (−1.72, 2.00) 58 0.01 0.88
Excluded trial
 DENERHTN 510/351 −0.32 (−2.21, 1.56) 52 0.04 0.74
 DENERVHTA 547/391 −0.36 (−2.03, 1.32) 47 0.07 0.68
 OSLO 549/394 −0.17 (−2.07, 1.74) 59 0.02 0.86
 Prague-15 506/350 0.36 (−1.77, 2.49) 63 0.009 0.74
 ReSET 523/371 0.06 (−2.02, 2.15) 63 0.009 0.95
 SYMPLICITY HTN-2 538/379 0.48 (−1.36, 2.31) 57 0.02 0.61
 SYMPLICITY HTN-3 229/242 0.39 (−1.89, 2.67) 61 0.01 0.74
 SYMPLICITY HTN-Japan 536/385 0.56 (−1.35, 2.47) 57 0.02 0.56
 SYMPLICITY HTN-Flex 526/369 0.31 (−1.90, 2.51) 63 0.008 0.79

DBP: Diastolic blood pressure; CI: Confidence interval; C: Control group; Phet: Significance for the heterogeneity test; Pz: Significance for the pooled effect size; R: Renal denervation group.