Skip to main content
. 2005 Feb 7;102(8):2886–2891. doi: 10.1073/pnas.0409872102

Fig. 1.

Fig. 1.

CD56 phenotype and function of activated CD56– NK cells. (A) Separation of CD56– and CD56+ subsets in total freshly isolated NK cells obtained from a viremic HIV-infected patient and recovery of CD56 expression upon stimulation with rIL-2 in vitro. (B) Spontaneous cytolytic activity against the K562 cell line of NK cells activated with rIL-2 for 6 days at various effector-to-target (E/T) ratios. Data represent the average lytic activity obtained by using CD56+ (green squares) versus CD56– (red circles) NK cells from 48 HIV-viremic patients. (C) Representative example of cytofluorometric analysis with CD56-PE/annexin V-FITC of CD56+ (left green plot) and CD56– (right red plot) NK cells after 6 days of stimulation with rIL-2. (D) Proliferation of CD56+ (green diamond) and CD56– (red circle) NK cell subsets at different cell numbers per well after stimulation with rIL-2 for 6 days. Data are represented as the average [3H]thymidine cpm of experiments conducted with cells from 48 patients.