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. Author manuscript; available in PMC: 2018 Jul 15.
Published in final edited form as: Biochem Pharmacol. 2017 Apr 9;136:86–98. doi: 10.1016/j.bcp.2017.03.025

Figure 6. Effect of GYY4137 on LDHA and LDHB activity of HCT116 cell extracts.

Figure 6

HCT116 cells (either with scrambled siRNA treatment or with siRNA-mediated LDHA silencing) were treated with 0.1–1 mM GYY4137 for 24 h and total cell lysates were collected. LDHA (A) or LDHB (B) enzymatic activities were measured as described in Materials and Methods. n = 4–6, for each group (A); n = 3–6, for each group (B); *P < 0.05 vs. untreated siRNA group, #P < 0.05 vs. untreated siLDHA group (based on two-way ANOVA corrected with Tukey’s post-hoc test).