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. Author manuscript; available in PMC: 2018 May 10.
Published in final edited form as: Cell Host Microbe. 2017 May 10;21(5):592–602.e4. doi: 10.1016/j.chom.2017.04.002

Figure 3. ARM transplantation restores resistance against VRE during antibiotic treatment.

Figure 3

(A) Prevention and (B) clearance of VRE colonization following PBS or ARM administration to ampicillin-treated mice. Three doses of ARM or PBS were administered daily by oral gavage to C57BL/6 ampicillin-treated mice before VRE challenge (A) or starting on the third day of VRE colonization (B). Fecal pellets were collected at the indicated time points for VRE quantification (n = 6–12 mice per group). Blue bar denotes continuous ampicillin treatment in the drinking water. (C) Clearance of VRE colonization following PBS or ASM administration measured in feces. C57BL/6 mice were challenged with VRE on the seventh day of ampicillin treatment, at which point treatment was stopped. The first of 3 doses of PBS or ASM was administered on day 3 post VRE challenge. L.o.D., limit of detection. CFU, colony-forming units.