Table 2.

Listing of all serious adverse events, regardless of relationship to study drug

Planned dose level (mg/m2)	SAE Preferred Term	Relationship to Study Drug
1.2	Multi-organ failure	No
1.2	Pneumonia	No
1.2	Bacteremia	No
1.2	Pneumonia fungal	No
1.2	Febrile neutropenia	No
1.2	Echocardiogram abnormal	Yes
1.7	Pulmonary embolism	No
1.7	Deep vein thrombosis	No
1.7	Febrile neutropenia	No
1.7	Staphylococcal sepsis	No
1.7	Disease progression	No
2.4	Perirectal abscess	No
2.4	Febrile neutropenia	No
2.4	Anemia	No
2.4	Disease progression	No
2.4	Septic shock	No
4.8	Bone pain	No
4.8	Febrile neutropenia	No
4.8	Disease progression	No
9.6	Pneumonia	No
9.6	Bacteremia	No
9.6	Asthenia	No
14.4	Disease progression	No
14.4	Sinusitis fungal	No
14.4	Sepsis	No