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. 2017 Jul;27(7):1099–1111. doi: 10.1101/gr.214775.116

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© 2017 Kan et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 5. — Mechanisms of paired-nick–induced PGE using the S ODNs. (A) Repair of the PAM-out double nicks via SDSA. (B) Repair of the PAM-in double nicks via ssDI. All schematic elements are colored and defined as in the legend to Figure 3.