Table S3.

GO enrichment analysis of genes positively correlated in Fig. 4D

GO enrichment annotation	Fold enrichment	P value
GO molecular function complete
ATP-dependent RNA helicase activity	5.64	1.62E-02
RNA binding	1.80	4.12E-04
Ion binding	1.29	7.36E-03
Protein binding	1.21	1.33E-04
GO biological function complete
tRNA metabolic process	3.92	3.20E-03
mRNA processing	2.58	6.83E-03
DNA metabolic process	2.29	4.11E-04
Chromosome organization	2.00	4.28E-03
Cellular nitrogen compound biosynthetic process	1.44	1.75E-02
Macromolecule modification	1.44	4.97E-02
Cellular macromolecule biosynthetic process	1.43	1.79E-02
Cellular protein metabolic process	1.42	4.21E-02
GO cellular component complete
Aminoacyl-tRNA synthetase multienzyme complex	27.46	2.10E-02
Nuclear chromosome, telomeric region	4.13	3.09E-02
Nuclear body	2.23	7.82E-04
Catalytic complex	2.01	1.05E-05
Mitochondrion	1.72	9.15E-04
Cytosol	1.41	8.29E-05
Reactome pathways
Gene expression	1.74	7.40E-04