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. 2017 Jul 3;12(7):e0180259. doi: 10.1371/journal.pone.0180259

Fig 10. Inhibition of bradykinin B(2) receptor does not affect the trypsin mediated increase in TER.

Fig 10

A. SCBN cells were mounted in Ussing chambers and treated basolaterally with the bradykinin B(2) receptor antagonist (10 μM) for 30 minutes then treated basolaterally with 50 nM bradykinin to determine the lowest dose of antagonist that blocks the chloride secretion. B. SCBN cells in Ussing chambers were treated apically with 10 μM antagonist for 30 minutes then stimulated apically with 45 BAU/mL trypsin. Tracing representative of n = 3. C. Percent increase in TER 15 minutes after trypsin addition normalized to the uninhibited control were determined. One sample T-test indicated no significant differences.