Fig 6. Effects of isoflurane on the release of cytokines in the lung following LPS challenge.

Experimental protocols of induction and time course of resolution of lung inflammation post-LPS or vehicle (CON) challenge in wild type mice were shown as Fig 5A. Mice were exposed to 1.0 MAC isoflurane (ISO) in an airtight box for 1 h. (A-D) The levels of TNF-α (A), IL-6 (B), TGF-β1 (C) and IL-10 (D) in BAL fluid measured by ELISA. n = 6 animals/group/time point. *P < 0.05 vs. corresponding LPS groups.