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. Author manuscript; available in PMC: 2017 Jul 3.
Published in final edited form as: Crit Rev Oncog. 2015;20(5-6):373–390. doi: 10.1615/CritRevOncog.v20.i5-6.100

FIG. 2.

FIG. 2

Tumor expression of ERβ1 associates with reduced overall survival (OS) in TNBC specimens from the clinic. TNBCs from three African-American and 11 Caucasian women were scored for nuclear (using IHC with validated antibody anti-ERβ1 antibody PPG5/10 (AbDSerotec). Allred scores >2 are denoted as positive. In this group of patients with advanced TNBC, overall survival (OS) was significantly worse for TNBC patients with high nuclear ERβ1 (positive) as compared to those with low (negative) ERβ1 (p < 0.001). We note that TNBCs from all three African-American women were high ERβ1-positive. (Reprinted with permission from the Hindawi Publishing Corporation, Copyright 2015).39