Table 5. Single nucleotide polymorphisms associating with dichotomous tuberculin skin test status below a 5x10-5 p-value using a dominant genetic model in the Ugandan cohort* (n = 199).
SNP | Chr. | Minor Allele | MAF | Odds Ratio | 95% Confidence Interval | p value | Nearest gene |
---|---|---|---|---|---|---|---|
rs877356 | 5 | T | 0.2337 | 0.171 | (0.078, 0.373) | 9.18E-06 | SLC25A48/IL9 |
rs654718 | 11 | G | 0.2136 | 0.190 | (0.089, 0.406) | 1.81E-05 | MRE11A |
rs7944514 | 11 | C | 0.4121 | 5.284 | (2.457, 11.360) | 2.03E-05 | POLD3 |
rs7837658 | 8 | T | 0.4472 | 4.842 | (2.319, 10.110) | 2.67E-05 | RNF19A |
* adjusted for 10 principal components and sex