TABLE 5.

Test Characteristics of the YOS Score >6 and >10 as Well as Unstructured Clinician Suspicion ≥1% and ≥5% for the Identification of Infants With any SBI Overall Stratified by Patient Age (0–28 vs 29–60 d of Age)

	Sensitivity, % (95% CI)	Specificity, % (95% CI)	Negative Predictive Value, % (95% CI)	Likelihood Ratio +, % (95% CI)	Likelihood Ratio, −, % (95% CI)
YOS > 6	0.39 (0.35–0.44)	0.66 (0.64–0.67)	0.91 (0.90–0.92)	1.15 (1.01–1.30)	0.92 (0.85–1.00)
0–28 d	0.40 (0.33–0.48)	0.65 (0.62–0.68)	0.88 (0.85–0.90)	1.16 (0.96–1.40)	0.91 (0.81–1.03)
29–60 d	0.38 (0.32–0.45)	0.66 (0.64–0.68)	0.93 (0.91–0.94)	1.13 (0.96–1.33)	0.93 (0.84–1.03)
YOS > 10	0.12 (0.09–0.15)	0.90 (0.89–0.91)	0.90 (0.89–0.91)	1.12 (0.85–1.47)	0.99 (0.95–1.02)
0–28 d	0.14 (0.09–0.20)	0.89 (0.87–0.91)	0.87 (0.85–0.89)	1.30 (0.89–1.91)	0.96 (0.91–1.02)
29–60 d	0.10 (0.06–0.14)	0.90 (0.89–0.91)	0.92 (0.91–0.93)	0.96 (0.64–1.42)	1.01 (0.96–1.05)
Suspicion > 1%	0.76 (0.71–0.80)	0.38 (0.36–0.39)	0.94 (0.92–0.95)	1.21 (1.14–1.29)	0.65 (0.55–0.77)
0–28 d	0.74 (0.68–0.80)	0.33 (0.31–0.36)	0.90 (0.86–0.92)	1.11 (1.01–1.22)	0.77 (0.60–1.00)
29–60 d	0.77 (0.71–0.82)	0.40 (0.38–0.41)	0.95 (0.94–0.96)	1.27 (1.18–1.37)	0.59 (0.47–0.74)
Suspicion > 5%	0.34 (0.30–0.39)	0.80 (0.79–0.82)	0.92 (0.91–0.93)	1.76 (1.52–2.03)	0.82 (0.76–0.87)
0–28 d	0.38 (0.31–0.45)	0.76 (0.74–0.79)	0.89 (0.87–0.91)	1.59 (1.29–1.96)	0.82 (0.73–0.92)
29–60 d	0.32 (0.26–0.38)	0.82 (0.81–0.84)	0.93 (0.92–0.94)	1.80 (1.47–2.20)	0.83 (0.76–0.90)