Table 1.
Baseline Demographic Characteristics for MCI Reversion and Progression Groups
| All Subjects (n = 596, 100%) |
Reversion (n = 175, 29.4%) |
Progression (n = 421, 70.6%) |
|||
|---|---|---|---|---|---|
|
| |||||
| Mean ± SD or N (%) | t | p-value | |||
| Age (years) | 74.07 ± 8.95 | 71.45 ± 9.07 | 75.16 ± 8.68 | −4.69 | <.001 |
| Education (years)* | 15.56 ± 3.06 | 15.75 ± 3.05 | 15.48 ± 3.07 | .96 | .336 |
|
| |||||
| χ2 | p-value | ||||
|
| |||||
| APOE ε4 Allele* | 25.88 | <.001 | |||
| 0 copies | 234 (49.6%) | 93 (67.9%) | 141 (42.1%) | ||
| ≥1 copy | 238 (50.4%) | 44 (32.1%) | 194 (57.9%) | ||
| Gender | 7.20 | .009 | |||
| Female | 300 (50.3%) | 103 (58.9%) | 197 (46.8%) | ||
| Male | 296 (49.7%) | 72 (41.1%) | 224 (53.2%) | ||
| Ethnicity | 3.70 | .076 | |||
| Hispanic | 26 (4.4%) | 12 (6.9%) | 14 (3.3%) | ||
| Non-Hispanic | 570 (95.6%) | 163 (93.1%) | 407 (96.7%) | ||
| Race* | 17.00 | .005 | |||
| White | 509 (85.5%) | 137 (78.3%) | 372 (88.6%) | ||
| Black/African Am. | 59 (9.9%) | 30 (17.1%) | 29 (6.9%) | ||
| Asian | 18 (3.0%) | 7 (4.0%) | 11 (2.7%) | ||
| Native Am./Alaskan | 1 (0.2%) | 0 (0.0%) | 1 (0.2%) | ||
| Native Hawaiian/Pac. Isl. | 1 (0.2%) | 0 (0.0%) | 1 (0.2%) | ||
| Other | 7 (1.2%) | 1 (0.6%) | 6 (1.4%) | ||
| Marital Status* | 9.35 | .003 | |||
| Married | 422 (70.9%) | 108 (62.1%) | 314 (74.6%) | ||
| Unmarried | 173 (29.1%) | 66 (37.9%) | 107 (25.4%) | ||
| MCI Subtype | 38.69 | <.001 | |||
| Amnestic | 504 (84.6%) | 123 (70.3%) | 381 (90.5%) | ||
| Nonamnestic | 92 (15.4%) | 52 (29.7%) | 40 (9.5%) | ||
| Source of Cognitive Complaint* | 117.70 | <.001 | |||
| Subject-Report Only | 48 (9.5%) | 30 (26.8%) | 18 (4.6%) | ||
| Informant-Report Only | 53 (10.4%) | 12 (10.7%) | 41 (10.4%) | ||
| Both Subject and Informant | 406 (80.1%) | 70 (62.5%) | 336 (85.0%) | ||
Notes: MCI = Mild Cognitive Impairment. APOE ε4 = Apolipoprotein E Allele 4. MCI Subtype Amnestic = Impairment in memory (single- or multi-domain). MCI Subtype Nonamnestic = Non-memory impairment (single- or multi-domain).
*
Education data for 1 participant, Race data for 1 participant, Marital Status data for 1 participant, APOE ε4 data for 124 participants, and Source of Cognitive Complaint data for 89 participants were not available.